![]() The following medications may interact with metoprolol tartrate or metoprolol succinate. treatment with propranolol or metoprolol, topiramate or flunarizine. ![]() ![]() Adverse Effects Common adverse effects of cardio-selective beta-blockers include bradycardia, decreased exercise capacity, hypotension, atrioventricular nodal block, and heart failure. Metoprolol (Lopressor, Toprol-XL) Considerations for Use US/FDA Approved Indication: Heart Rate Control for Atrial Fibrillation Black Box Warning Abrupt cessation may exacerbate angina pectoris and MI. 60/185 (32.4) converted to 50 responders in at least half the visits and. Make sure you tell your doctor about all prescription and over-the-counter drugs, supplements, and herbs you take before you start treatment with a new medication. There is prolongation of the elimination half-life of metoprolol in patients with hepatic failure. Both drugs share similar drug interactions.
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